Article
The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor.
Cell - 17 Nov 2006
Han Junhai, Gong Ping, Reddig Keith, Mitra Mirna, Guo Peiyi, Li Hong-Sheng
Abstract excerpt
Control of membrane-receptor activity is required not only for the accuracy of sensory responses, but also to protect cells from excitotoxicity. Here we report the isolation of two noncomplementary fly mutants with slow termination of photoresponses. Genetic and electrophysiological analyses of the mutants revealed a defect in the deactivation of rhodopsin, a visual G protein-coupled receptor (GPCR). The mutant...
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