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Article

p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping.

Neuron - 11 Sept 2008

Lim Yoo-Shick, McLaughlin Todd, Sung Tsung-Chang, Santiago Alicia, Lee Kuo-Fen, O'Leary Dennis D M

Abstract excerpt

Reverse signaling by ephrin-As upon binding EphAs controls axon guidance and mapping. Ephrin-As are GPI-anchored to the membrane, requiring that they complex with transmembrane proteins that transduce their signals. We show that the p75 neurotrophin receptor (NTR) serves this role in retinal axon...

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Source

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Identifiers

PMID: 18786358
DOI: 10.1016/j.neuron.2008.07.032
PMCID: PMC2677386

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18786358-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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