Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cancer incidence in relatives of British Fanconi Anaemia patients.

BMC cancer - 11 Sept 2008

Tischkowitz Marc, Easton Douglas F, Ball Jan, Hodgson Shirley V, Mathew Christopher G

Abstract excerpt

BACKGROUND: Fanconi anemia (FA) is an autosomal recessive DNA repair disorder with affected individuals having a high risk of developing acute myeloid leukaemia and certain solid tumours. Thirteen complementation groups have been identified and the genes for all of these are known (FANCA, B, C, D1/BRCA2, D2, E, F, G, I, J/BRIP1, L, M and N/PALB2). Previous studies of cancer incidence in relatives of Fanconi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Cohort Studies
Share to Family Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fanconi Anemia

Share to Genetic Predisposition to Disease

Share to Incidence

Share to Neoplasms

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 18786261
DOI: 10.1186/1471-2407-8-257
PMCID: PMC2556683

Genes

BRCA2
BRIP1
FANCA
PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cancer incidence in relatives of British Fanconi Anaemia patients.PMID 18786261Read ↗

Risk of cancer in heterozygous relatives of patients with Fanconi anemia.Semantic proximity Read ↗

Fanconi anaemia genes and susceptibility to cancer.Semantic proximity Read ↗

Genetic heterogeneity among Fanconi anemia heterozygotes and risk of cancer.Semantic proximity Read ↗

Finnish Fanconi anemia mutations and hereditary predisposition to breast and prostate cancer.Semantic proximity Read ↗

Fanconi anaemia, BRCA2 mutations and childhood cancer: a developmental perspective from clinical and epidemiological observations with implications for genetic counselling.Semantic proximity Read ↗

Cancer in Fanconi anemia, 1927–2001Semantic proximity Read ↗

Concordant and discordant familial cancer: Familial risks, proportions and population impact.Semantic proximity Read ↗

Polymorphic variations in the FANCA gene in high-risk non-BRCA1/2 breast cancer individuals from the French Canadian population.Semantic proximity Read ↗

Evaluation of Fanconi anaemia genes FANCA, FANCC and FANCL in cervical cancer susceptibility.Semantic proximity Read ↗

Cancer in patients with ataxia-telangiectasia and in their relatives in the nordic countries.Semantic proximity Read ↗

Development of primary early-onset colorectal cancers due to biallelic mutations of the FANCD1/BRCA2 gene.Semantic proximity Read ↗

Incidence of Cancer in 161 Families Affected by Ataxia–TelangiectasiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.