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Article

Polymorphic variations in the FANCA gene in high-risk non-BRCA1/2 breast cancer individuals from the French Canadian population.

Molecular oncology - 1 Feb 2013

Litim Nadhir, Labrie Yvan, Desjardins Sylvie, Ouellette Geneviève, Plourde Karine, Belleau Pascal, Durocher Francine

Abstract excerpt

The majority of genes associated with breast cancer susceptibility, including BRCA1 and BRCA2 genes, are involved in DNA repair mechanisms. Moreover, among the genes recently associated with an increased susceptibility to breast cancer, four are Fanconi Anemia (FA) genes: FANCD1/BRCA2, FANCJ/BACH1/BRIP1, FANCN/PALB2 and FANCO/RAD51C. FANCA is implicated in DNA repair and has been shown to interact directly with...

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Source

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Identifiers

PMID: 23021409
DOI: 10.1016/j.molonc.2012.08.002
PMCID: PMC5528405

Genes

FANCA
BRCA1
BRCA2
BACH1
BRIP1
FANCB
FANCD2
FANCI
FANCM
PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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