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Article

Low Ca2+ buffering in hypoglossal motoneurons of mutant SOD1 (G93A) mice.

Neuroscience letters - 21 Nov 2008

von Lewinski Friederike, Fuchs Julia, Vanselow Bodo K, Keller Bernhard U

Abstract excerpt

Mutations in the Cu/Zn superoxide dismutase (SOD1) gene are associated with amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder characterized by a selective degeneration of brainstem and spinal motoneurons. The pathomechanism of degeneration is still incompletely understood, but includes a disruption in cellular Ca2+ homeostasis. Here we report a quantitative microfluorometric analysis of the...

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Source

Identifiers

PMID: 18782598
DOI: 10.1016/j.neulet.2008.08.084

Genes

SOD1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Low Ca2+ buffering in hypoglossal motoneurons of mutant SOD1 (G93A) mice.PMID 18782598Read ↗

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