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Article

Association of APOA5 -1131T>C and S19W gene polymorphisms with both mild hypertriglyceridemia and hyperchylomicronemia in type 2 diabetic patients.

Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2008

Charriere Sybil, Bernard Sophie, Aqallal Mahdi, Merlin Micheline, Billon Stéphane, Perrot Laurence, Le Coquil Elodie, Sassolas Agnès, Moulin Philippe, Marcais Christophe

Abstract excerpt

BACKGROUND: Two minor apolipoprotein A5 (APOA5) gene haplotypes, represented by -1131T>C and S19W polymorphisms, are strong determinants of plasma triglyceride (TG) concentration variability across human populations. Hypertriglyceridemia is frequent in type 2 diabetes (T2D) and hyperchylomicronemia is not uncommon. METHODS: We investigated the association of -1131T>C and S19W polymorphisms with diabetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18468520
DOI: 10.1016/j.cca.2008.04.013

Genes

APOA5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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