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Article

Mutation of murine adenylate kinase 7 underlies a primary ciliary dyskinesia phenotype.

American journal of respiratory cell and molecular biology - 1 Mar 2009

Fernandez-Gonzalez Angeles, Kourembanas Stella, Wyatt Todd A, Mitsialis S Alex

Abstract excerpt

Primary ciliary dyskinesia (PCD) is a genetically and phenotypically heterogeneous disorder, characterized by progressive development of bronchiectasis, inflammation, and features characteristic of chronic obstructive pulmonary disease. We report here that a murine mutation of the evolutionarily conserved adenylate kinase 7 (Ak7) gene results in animals presenting with pathological signs characteristic of PCD,...

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Identifiers

PMID: 18776131
DOI: 10.1165/rcmb.2008-0102OC
PMCID: PMC2645528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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