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Article

Static respiratory cilia associated with mutations in Dnahc11/DNAH11: a mouse model of PCD.

Human mutation - 1 Mar 2012

Lucas Jane S, Adam Elizabeth C, Goggin Patricia M, Jackson Claire L, Powles-Glover Nicola, Patel Saloni H, Humphreys James, Fray Martin D, Falconnet Emilie, Blouin Jean-Louis, Cheeseman Michael T, Bartoloni Lucia, Norris Dominic P, Lackie Peter M

Abstract excerpt

Primary ciliary dyskinesia (PCD) is an inherited disorder causing significant upper and lower respiratory tract morbidity and impaired fertility. Half of PCD patients show abnormal situs. Human disease loci have been identified but a mouse model without additional deleterious defects is elusive. The inversus viscerum mouse, mutated at the outer arm dynein heavy chain 11 locus (Dnahc11) is a known model of...

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Identifiers

PMID: 22102620
DOI: 10.1002/humu.22001

Genes

DNAH11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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