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Article

Titin Diversity—Alternative Splicing Gone Wild

1 Jan 2010

Abstract excerpt

Titin is an extremely large protein found in highest concentrations in heart and skeletal muscle. The single mammalian gene is expressed in multiple isoforms as a result of alternative splicing. Although titin isoform expression is controlled developmentally and in a tissue specific manner, the vast number of potential splicing pathways far exceeds those described in any other alternatively spliced gene. Over 1...

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Identifiers

PMID: 20339475
DOI: 10.1155/2010/753675

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