Article
Paz2 and 13 other <i>PAZ</i> gene products regulate vacuolar engulfment of peroxisomes during micropexophagy
1 Jan 2002
Abstract excerpt
BACKGROUND: In the methylotrophic yeast Pichia pastoris, peroxisomes can be selectively degraded through direct engulfment by the vacuole in a process known as micropexophagy, but the mechanism of micropexophagy is not known. RESULTS: To gain molecular insights into micropexophagy, we used fluorescence time-lapse microscopy, coupled with gene-tagging mutagenesis to isolate P. pastoris mutants defective in...