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Article

Strain variation in ppGpp concentration and RpoS levels in laboratory strains of Escherichia coli K-12.

Microbiology (Reading, England) - 1 Sept 2008

Spira Beny, Hu Xuye, Ferenci Thomas

Abstract excerpt

Laboratory strains and natural isolates of Escherichia coli differ in their level of stress resistance due to strain variation in the level of the sigma factor sigma(S) (or RpoS), the transcriptional master controller of the general stress response. We found that the high level of RpoS in one laboratory strain (MC4100) was partially dependent on an elevated basal level of ppGpp, an alarmone responding to stress...

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Share to Escherichia coli K12
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Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18757823
DOI: 10.1099/mic.0.2008/018457-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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