Article
The constancy of global regulation across a species: the concentrations of ppGpp and RpoS are strain-specific in Escherichia coli.
BMC microbiology - 25 Mar 2011
Ferenci Thomas, Galbiati Heloisa Filus, Betteridge Thu, Phan Katherine, Spira Beny
Abstract excerpt
BACKGROUND: Sigma factors and the alarmone ppGpp control the allocation of RNA polymerase to promoters under stressful conditions. Both ppGpp and the sigma factor σS (RpoS) are potentially subject to variability across the species Escherichia coli. To find out the extent of strain variation we measured the level of RpoS and ppGpp using 31 E. coli strains from the ECOR collection and one reference K-12 strain....
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