Article
Pedigree with frontotemporal lobar degeneration--motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9.
BMC neurology - 29 Aug 2008
Luty Agnes A, Kwok John B J, Thompson Elizabeth M, Blumbergs Peter, Brooks William S, Loy Clement T, Dobson-Stone Carol, Panegyres Peter K, Hecker Jane, Nicholson Garth A, Halliday Glenda M, Schofield Peter R
Abstract excerpt
BACKGROUND: Frontotemporal lobar degeneration (FTLD) represents a clinically, pathologically and genetically heterogenous neurodegenerative disorder, often complicated by neurological signs such as motor neuron-related limb weakness, spasticity and paralysis, parkinsonism and gait disturbances. Linkage to chromosome 9p had been reported for pedigrees with the neurodegenerative disorder, frontotemporal lobar...
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