Article
Distribution of pneumococcal surface protein A families 1 and 2 among Streptococcus pneumoniae isolates from children in finland who had acute otitis media or were nasopharyngeal carriers.
Clinical and vaccine immunology : CVI - 1 Oct 2008
Melin Merit M, Hollingshead Susan K, Briles David E, Hanage William P, Lahdenkari Mika, Kaijalainen Tarja, Kilpi Terhi M, Käyhty Helena M
Abstract excerpt
PspA is a structurally variable surface protein important to the virulence of pneumococci. PspAs are serologically cross-reactive and exist as two major families. In this study, we determined the distribution of PspA families 1 and 2 among pneumococcal strains isolated from the middle ear fluid (MEF) of children with acute otitis media and from nasopharyngeal specimens of children with pneumococcal carriage. We...
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