Article
Invasive Streptococcus pneumoniae isolates from Argentinian children: serotypes, families of pneumococcal surface protein A (PspA) and genetic diversity.
Epidemiology and infection - 1 Apr 2004
Mollerach M, Regueira M, Bonofiglio L, Callejo R, Pace J, Di Fabio J L, Hollingshead S, Briles D
Abstract excerpt
PspA is an antigenically variable virulence factor of Streptococcus pneumoniae that inhibits complement deposition and is a potential candidate for human vaccines. Of 64 published strains 96% are in PspA families 1 and 2; optimal protection is family-specific. Effective development of a PspA-cont...
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