Article
Genetic diversity of PspA types among nasopharyngeal isolates collected during an ongoing surveillance study of children in Brazil.
Journal of clinical microbiology - 1 Aug 2006
Pimenta Fabiana Cristina, Ribeiro-Dias Fátima, Brandileone Maria Cristina C, Miyaji Eliane N, Leite Luciana C C, Sgambatti de Andrade Ana Lúcia S
Abstract excerpt
Pneumococcal surface protein A (PspA) has been considered a potential candidate for human vaccines because of its serotype-independent protective immunity. Nasopharyngeal (NP) pneumococcal colonization is highly prevalent in infants and precedes the invasive disease. Thus, prevention of NP colonization may reduce the burden of pneumococcal disease in children. Scarce information focusing on PspA from pneumococcal...
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