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Article

High throughput non-invasive determination of foetal Rhesus D status using automated extraction of cell-free foetal DNA in maternal plasma and mass spectrometry.

Archives of gynecology and obstetrics - 1 Apr 2009

Grill Simon, Banzola Irina, Li Ying, Rekhviashvili Tea, Legler Tobias J, Müller Sina P, Zhong Xiao Yan, Hahn Sinuhe, Holzgreve Wolfgang

Abstract excerpt

PURPOSE: To examine the potential high throughput capability and efficiency of an automated DNA extraction system in combination with mass spectrometry for the non-invasive determination of the foetal Rhesus D status. METHODS: A total of 178 maternal plasma samples from RHD-negative pregnant women were examined, from which DNA was extracted using the automated Roche MagNA Pure system. Presence of the foetal RHD...

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Source

Identifiers

PMID: 18751991
DOI: 10.1007/s00404-008-0774-5

Genes

RHD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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