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Article

A "FLP-Out" system for controlled gene expression in Caenorhabditis elegans.

Genetics - 1 Sept 2008

Voutev Roumen, Hubbard E Jane Albert

Abstract excerpt

We present a two-part system for conditional FLP-out of FRT-flanked sequences in Caenorhabditis elegans to control gene activity in a spatially and/or temporally regulated manner. Using reporters, we assess the system for efficacy and demonstrate its use as a cell lineage marking tool. In addition, we construct and test a dominant-negative form of hlh-12, a gene that encodes a basic helix-loop-helix (bHLH)...

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Identifiers

PMID: 18723890
DOI: 10.1534/genetics.108.090274
PMCID: PMC2535667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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