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Article

Developmental regulation of neurotransmitter phenotype through tetrahydrobiopterin.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Nov 2002

Habecker Beth A, Klein Michael G, Sundgren Nathan C, Li Wei, Woodward William R

Abstract excerpt

During development, sympathetic neurons innervating rodent sweat glands undergo a target-induced change in neurotransmitter phenotype from noradrenergic to cholinergic. Although the sweat gland innervation in the adult mouse is cholinergic and catecholamines are absent, these neurons continue to express tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine synthesis. The developmental suppression...

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Identifiers

PMID: 12417669
PMCID: PMC6758055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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