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Article

Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves.

Journal of the autonomic nervous system - 6 May 1996

Cowen T, Thrasivoulou C, Shaw S A, Abdel-Rahman T A

Abstract excerpt

Contact with sweat gland acini causes sympathetic neurons to switch from a catecholaminergic to a cholinergic phenotype during development and following experimental manipulations. Substantial reductions of cholinergic innervation have been shown in the sweat glands of ageing rats and humans. Using in oculo transplantation, we have now studied whether sweat gland target tissues retain the capacity to regulate...

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PMID: 8738308
DOI: 10.1016/0165-1838(95)00127-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves.PMID 8738308Read ↗

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