Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves.

doi:10.1016/0165-1838(95)00127-1

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Article

Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves.

Journal of the autonomic nervous system - 6 May 1996

Cowen T, Thrasivoulou C, Shaw S A, Abdel-Rahman T A

Abstract excerpt

Contact with sweat gland acini causes sympathetic neurons to switch from a catecholaminergic to a cholinergic phenotype during development and following experimental manipulations. Substantial reductions of cholinergic innervation have been shown in the sweat glands of ageing rats and humans. Usi...

Topics

Adrenergic Fibers
Aging
Animals
Cholinergic Fibers
Fluorescent Antibody Technique
Fluorescent Dyes
Nerve Regeneration
Phenotype
Rats
Rats, Sprague-Dawley
Stilbamidines
Superior Cervical Ganglion
Sweat Glands
Sympathectomy
Vasoactive Intestinal Peptide

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Open in PubMed

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PMID: 8738308
DOI: 10.1016/0165-1838(95)00127-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8738308-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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