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Article

Target regulation of neurotransmitter phenotype.

Trends in neurosciences - 1 Aug 1990

Landis S C

Abstract excerpt

Studies of sympathetic neurons developing in cell culture revealed a surprising degree of transmitter plasticity and established the role of environmental factors in determining transmitter choice. The sympathetic neurons that innervate sweat glands undergo a change in neurotransmitter phenotype from noradrenergic to cholinergic during normal development similar to that observed in culture. Cross-innervation...

Topics

Animals
Neuronal Plasticity
Neurotransmitter Agents
Phenotype
Stimulation, Chemical
Sweat Glands

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1699321
DOI: 10.1016/0166-2236(90)90147-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1699321-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Target regulation of neurotransmitter phenotype.PMID 1699321Read ↗

Target determination of neurotransmitter phenotype in sympathetic neurons.Semantic proximity Read ↗

Sweat gland innervation is pioneered by sympathetic neurons expressing a cholinergic/noradrenergic co-phenotype in the mouse.Semantic proximity Read ↗

Cell interactions that determine sympathetic neuron transmitter phenotype and the neurokines that mediate them.Semantic proximity Read ↗

Development of neurotransmitter phenotypes in sympathetic neurons.Semantic proximity Read ↗

Generating diversity: Mechanisms regulating the differentiation of autonomic neuron phenotypes.Semantic proximity Read ↗

Noradrenergic regulation of cholinergic differentiation.Semantic proximity Read ↗

The differentiation of the neurotransmitter phenotypes in chick sympathetic neurons.Semantic proximity Read ↗

Target influences on transmitter choice by sympathetic neurons developing in the anterior chamber of the eye.Semantic proximity Read ↗

Neurotransmitter phenotype-specific expression changes in developing sympathetic neurons.Semantic proximity Read ↗

Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves.Semantic proximity Read ↗

Transplanted sweat glands from mature and aged donors determine cholinergic phenotype and altered density of host sympathetic nerves.Semantic proximity Read ↗

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