Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction.

Abstract excerpt

This article presents evidence suggesting that psychosocial stress may increase risk for psychosis, especially in the case of cumulative exposure. A heuristically useful framework to study the underlying mechanisms is the concept of "behavioral sensitization" that stipulates that exposure to psychosocial stress--such as life events, childhood trauma, or discriminatory experiences--may progressively increase the...

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