Article
The association between the survivin C-31G polymorphism and gastric cancer risk in a Chinese population.
Digestive diseases and sciences - 1 May 2009
Yang Li, Zhu Huaijun, Zhou Bo, Gu Haijuan, Yan Hongli, Tang Naping, Dong Hanzhang, Sun Qingmin, Cong Rihong, Chen Guoyu, Wang Bin
Abstract excerpt
INTRODUCTION: The C-31G polymorphism in the survivin promoter could de-repress the cell-cycle-dependent transcription of the human survivin gene, resulting in overexpression of survivin. This survivin mutation has only been studied on cervical carcinoma. However, no study has ever been conducted to evaluate the effect of the polymorphism on other cancers, including gastric cancer. METHODS: In this hospital-based,...
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