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Article

Identification of NLRP3 and TIPE2 as asthma biomarkers via integrative bioinformatics and Mendelian randomization.

Medicine - 6 Feb 2026

Bao Yuchun, Erboev Ahmadshoh, Huang Weina

Abstract excerpt

Asthma is a chronic inflammatory airway disease imposing a substantial global health burden. NLRP3 is an immune sensor involved in infection and cellular stress responses. Recent studies suggest that NLRP3 may be involved in the pathogenesis of asthma. We hypothesized that genetic variation in NLRP3 may contribute to asthma susceptibility. However, the causal relationship between NLRP3 and asthma still remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 41650104
DOI: 10.1097/MD.0000000000047467
PMCID: PMC12885742

Genes

NLRP3
TIPE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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