Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Specific tumour-associated methylation in normal human term placenta and first-trimester cytotrophoblasts

16 Aug 2008

Abstract excerpt

Human placentation displays many similarities with tumourigenesis, including rapid cell division, migration and invasion, overlapping gene expression profiles and escape from immune detection. Recent data have identified promoter methylation in the Ras association factor and adenomatous polyposis coli tumour suppressor genes as part of this process. However, the extent of tumour-associated methylation in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Pregnancy and preeclampsia studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18708652
DOI: 10.1093/molehr/gan046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Specific tumour-associated methylation in normal human term placenta and first-trimester cytotrophoblastsPMID 18708652Read ↗

Human placental trophoblast invasion and differentiation: a particular focus on Wnt signalingSemantic proximity Read ↗

The Early Pregnancy Human Placenta Shares Hypomethylation Patterns Characteristic of Solid TumorsSemantic proximity Read ↗

A case of intraplacental gestational choriocarcinoma; characterised by the methylation pattern of the early placenta and an absence of driver mutationsSemantic proximity Read ↗

Potential role of epigenetic mechanisms in regulation of trophoblast differentiation, migration, and invasion in the human placentaSemantic proximity Read ↗

Recent progress towards understanding the role of DNA methylation in human placental developmentSemantic proximity Read ↗

Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function.Semantic proximity Read ↗

Epigenetic changes regulating the epithelial-mesenchymal transition in human trophoblast differentiationSemantic proximity Read ↗

Epigenetic Changes Regulating Epithelial–Mesenchymal Plasticity in Human Trophoblast DifferentiationSemantic proximity Read ↗

Hypermethylation and loss of retinoic acid receptor responder 1 expression in human choriocarcinomaSemantic proximity Read ↗

A complex association between DNA methylation and gene expression in human placenta at first and third trimestersSemantic proximity Read ↗

Placental pseudo-malignancy from a DNA methylation perspective: unanswered questions and future directionsSemantic proximity Read ↗

The role of DNA methylation in human trophoblast differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.