Article
Breast cancer risk polymorphisms and interaction with ionizing radiation among U.S. radiologic technologists.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2008
Bhatti Parveen, Doody Michele M, Alexander Bruce H, Yuenger Jeff, Simon Steven L, Weinstock Robert M, Rosenstein Marvin, Stovall Marilyn, Abend Michael, Preston Dale L, Pharoah Paul, Struewing Jeffery P, Sigurdson Alice J
Abstract excerpt
Genome-wide association studies are discovering relationships between single-nucleotide polymorphisms and breast cancer, but the functions of these single-nucleotide polymorphisms are unknown and environmental exposures are likely to be important. We assessed whether breast cancer risk single-nucleotide polymorphisms interacted with ionizing radiation, a known breast carcinogen, among 859 cases and 1,083 controls...
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