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Article

Re-expression of transcription factor ATF5 in hepatocellular carcinoma induces G2-M arrest.

Cancer research - 15 Aug 2008

Gho Jennifer W-M, Ip Wai-Ki, Chan Kathy Y-Y, Law Priscilla T-Y, Lai Paul B-S, Wong Nathalie

Abstract excerpt

Transcription factors represent an important class of genes that play key roles in controlling cellular proliferation, cell cycle modulation, and attractive targets for cancer therapy. Here, we report on the novel finding of common ATF5 down-regulations in hepatocellular carcinoma (HCC), a highly malignant tumor with a dismal clinical course. Array-based mapping in HCC highlighted a high and consistent incidence...

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Source

Identifiers

PMID: 18701499
DOI: 10.1158/0008-5472.CAN-07-6469

Genes

ATF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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