Article
Failure to confirm an association between Epsin 4 and schizophrenia in a Japanese population.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2008
Richards Misty, Iijima Yoshimi, Shizuno Tomoko, Kamegaya Yoko, Hori Hiroaki, Omori Mayu, Arima Kunimasa, Saitoh Osamu, Kunugi Hiroshi
Abstract excerpt
Previous studies suggested that genetic variations in the 5' region of Epsin 4, a gene encoding enthoprotin on chromosome 5q33, are associated with schizophrenia. However, conflicting results have also been reported. We examined the possible association in a Japanese sample of 354 patients and 365 controls. Seventeen polymorphisms of Epsin 4 [3 microsatellites and 14 single nucleotide polymorphisms (SNPs)] were...
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