Article
No association of EGF polymorphism with schizophrenia in a Japanese population.
Neuroreport - 15 Mar 2005
Watanabe Yuichiro, Fukui Naoki, Muratake Tatsuyuki, Kaneko Naoshi, Someya Toshiyuki
Abstract excerpt
Epidermal growth factor (EGF) signal regulates the development of dopaminergic neurons and monoamine metabolism. It is suggested that EGF protein levels are decreased in the brain and blood of patients with schizophrenia. A recent study has reported that a polymorphism in EGF gene (rs4444903) is associated with schizophrenia in Finnish men. To confirm this association for another population in larger samples, we...
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