Article
A novel, non-functional, COL1A1 polymorphism is not associated with lumbar disk disease in young male Greek subjects unlike that of the Sp1 site.
Hormones (Athens, Greece) - 1 Jan 2000
Bei Thalia, Tilkeridis Constantinos, Garantziotis Stavros, Boikos Sosipatros, Kazakos Konstantinos, Simopoulos Constantinos, Stratakis Constantine
Abstract excerpt
OBJECTIVE: We recently reported the association of the Sp1 site polymorphism of the COL1A1 gene with lumbar disk disease (LDD). In the present study we searched for a different polymorphism of the COL1A1 gene (which is usually not in linkage disequilibrium with the Sp1 site) in subjects with LDD. DESIGN: Blood was collected from 24 Greek army recruits, aged 29+/-7.6 years, with LDD, and 66 healthy men, aged...
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