Article
The COL1A1 gene and acute soft tissue ruptures.
British journal of sports medicine - 1 Nov 2010
Collins Malcolm, Posthumus Michael, Schwellnus Martin P
Abstract excerpt
Three studies have suggested that the rare TT genotype of the functional Sp1 binding site polymorphism within intron 1 of COL1A1 is associated with cruciate ligament ruptures (CL), shoulder dislocations (SD) and/or Achilles tendon ruptures. Similar genotype distributions were reported for the control and the injury groups in all three studies. In this report, the data from these studies were combined and...
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