Article
Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk.
Leukemia research - 1 Feb 2009
Lee Kyoung-Mu, Ward Mary H, Han Sohee, Ahn Hyo Seop, Kang Hyoung Jin, Choi Hyung Soo, Shin Hee Young, Koo Hong-Hoe, Seo Jong-Jin, Choi Ji-Eun, Ahn Yoon-Ok, Kang Daehee
Abstract excerpt
We conducted a case-control study to evaluate the association between paternal smoking and childhood leukemia and to evaluate potential modification by polymorphisms in CYP1A1. Histologically confirmed childhood leukemia cases (n=164) and non-cancer controls (n=164) were recruited from three teaching hospitals in Seoul, Korea. Five single nucleotide polymorphisms in CYP1A1 (-17961T>C, -9893G>A, I462V, 1188C>T...
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