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Article

A life-span extending form of autophagy employs the vacuole-vacuole fusion machinery.

Autophagy - 1 Oct 2008

Tang Fusheng, Watkins Joseph W, Bermudez Maria, Gray Russell, Gaban Adam, Portie Ken, Grace Stephen, Kleve Maurice, Craciun Gheorghe

Abstract excerpt

While autophagy is believed to be beneficial for life-span extension, it is controversial which forms or aspects of autophagy are responsible for this effect. We addressed this topic by analyzing the life span of yeast autophagy mutants under caloric restriction, a longevity manipulation. Surpris...

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Identifiers

PMID: 18690010
DOI: 10.4161/auto.6556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18690010-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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