Article
Carnitine-dependent transport of acetyl coenzyme A in Candida albicans is essential for growth on nonfermentable carbon sources and contributes to biofilm formation.
Eukaryotic cell - 1 Apr 2008
Strijbis Karin, van Roermund Carlo W T, Visser Wouter F, Mol Els C, van den Burg Janny, MacCallum Donna M, Odds Frank C, Paramonova Ekaterina, Krom Bastiaan P, Distel Ben
Abstract excerpt
In eukaryotes, acetyl coenzyme A (acetyl-CoA) produced during peroxisomal fatty acid beta-oxidation needs to be transported to mitochondria for further metabolism. Two parallel pathways for acetyl-CoA transport have been identified in Saccharomyces cerevisiae; one is dependent on peroxisomal citrate synthase (Cit), while the other requires peroxisomal and mitochondrial carnitine acetyltransferase (Cat)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.