Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic viscoelasticity of actin cross-linked with wild-type and disease-causing mutant alpha-actinin-4.

Biophysical journal - 15 Nov 2008

Ward Sabine M Volkmer, Weins Astrid, Pollak Martin R, Weitz David A

Abstract excerpt

The actin cross-linker alpha-actinin-4 has been found to be indispensable for the structural and functional integrity of podocytes; deficiency or alteration of this protein due to mutations results in kidney disease. To gain insight into the effect of the cross-linker on cytoskeletal mechanics, w...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actinin
Share to Actins
Share to Binding Sites

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computer Simulation

Share to Elasticity

Share to Kidney Diseases

Share to Models, Chemical

Share to Viscosity

Source

Open in PubMed Open full text

Identifiers

PMID: 18689451
DOI: 10.1529/biophysj.108.131722
PMCID: PMC2576355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18689451-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic viscoelasticity of actin cross-linked with wild-type and disease-causing mutant alpha-actinin-4.PMID 18689451Read ↗

Nonlinear viscoelasticity of actin transiently cross-linked with mutant α-actinin-4.Semantic proximity Read ↗

Dynamic actin crosslinking governs the cytoplasm’s transition to fluid-like behaviorSemantic proximity Read ↗

Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity.Semantic proximity Read ↗

Viscoelasticity of intermediate filament networks.Semantic proximity Read ↗

Rheology of the CytoskeletonSemantic proximity Read ↗

Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretchSemantic proximity Read ↗

A single charge in the actin binding domain of fascin can independently tune the linear and non-linear response of an actin bundle network.Semantic proximity Read ↗

Modeling the assembly of the multiple domains of α-actinin-4 and its role in actin cross-linking.Semantic proximity Read ↗

The role of extracellular matrix viscoelasticity in development and diseaseSemantic proximity Read ↗

Role of actin-binding proteins in the regulation of cellular mechanicsSemantic proximity Read ↗

Modulating alpha-actinin-4 dynamics in podocytes.Semantic proximity Read ↗

Force-modulated structural landscape of the catch bonding F-actin crosslinker α-actinin-4Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.