Article
Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C.
Hepatology (Baltimore, Md.) - 1 Sept 2008
Cua Ian Homer Y, Hui Jason M, Kench James G, George Jacob
Abstract excerpt
UNLABELLED: The interaction between insulin resistance (IR), steatosis and genotype to fibrosis in chronic hepatitis C virus (HCV) infection has not been comprehensively assessed. We hypothesized that IR is a key mediator for the development of both steatosis and fibrosis in 346 untreated, nondiabetic patients solely infected with either genotype 1 or 3. We examined for genotype-specific interactions between IR,...
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