Article
In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: implications for therapy.
Journal of hepatology - 1 Dec 2003
Hickman Ingrid J, Powell Elizabeth E, Prins Johannes B, Clouston Andrew D, Ash Susan, Purdie David M, Jonsson Julie R
Abstract excerpt
BACKGROUND/AIMS: Host factors such as increased body mass index (BMI) and genotype-specific viral factors contribute to the development of steatosis in patients with chronic hepatitis C (HCV). We hypothesized that host metabolic factors associated with increased BMI may play a role in disease progression. METHODS: Fasting serum was collected from 160 patients with chronic HCV at the time of liver biopsy and 45...
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