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Development and Validation of a Quantitative PCR Assay for Diagnosis of Scedosporiosis

6 Aug 2008

Abstract excerpt

Scedosporium apiospermum and Scedosporium prolificans are fungal pathogens that can cause severe human infections, including disseminated mycosis in immunocompromised patients. Two real-time PCR (RT-PCR) assays for the diagnosis of these species were developed and validated for the classification of clinical strains and for the detection of DNA in clinical samples by use of a murine model of invasive infection. A...

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PMID: 18684999
DOI: 10.1128/jcm.00046-08

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