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Article

Performance of Targeted Fungal Sequencing for Culture-Independent Diagnosis of Invasive Fungal Disease

10 Aug 2017

Abstract excerpt

BACKGROUND: Identification of fungi causing invasive fungal disease (IFD) is critical for guiding antifungal therapy. We describe the performance and clinical impact of a targeted panfungal polymerase chain reaction (PCR) amplicon sequencing assay for culture-independent diagnosis of IFD. METHODS: Between January 2009 and September 2016, 233 specimens, consisting of fresh and formalin-fixed, paraffin-embedded...

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PMID: 29020284
DOI: 10.1093/cid/cix728

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