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Article

ExoU-induced procoagulant activity in Pseudomonas aeruginosa-infected airway cells.

The European respiratory journal - 1 Dec 2008

Plotkowski M C, Feliciano L F P, Machado G B S, Cunha L G, Freitas C, Saliba A M, de Assis M C

Abstract excerpt

The present study addressed the question whether ExoU, a Pseudomonas aeruginosa toxin with phospholipase A2 (PLA2) activity, may induce airway epithelial cells to overexpress tissue factor (TF) and exhibit a procoagulant phenotype. Cells from the human bronchial epithelial BEAS-2B line were infected with an ExoU-producing P. aeruginosa strain, pre-treated or not with the cytosolic PLA2 inhibitor methylarachidonyl...

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Source

Identifiers

PMID: 18684846
DOI: 10.1183/09031936.00086708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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