Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies

Abstract excerpt

In cystic fibrosis (CF) airways, Pseudomonas aeruginosa forms cellular aggregates called biofilms that are thought to contribute to chronic infection. To form aggregates, P. aeruginosa can use different mechanisms, each with its own pathogenic implications. However, how they form in vivo is controversial and unclear. One mechanism involves a bacterially produced extracellular matrix that holds the aggregates...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacterial biofilms and quorum sensing
• Share to Bacterial Genetics and Biotechnology
• Share to Cystic Fibrosis Research Advances