Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of the Y Chromosome: An Age-Related or Clonal Phenomenon in Acute Myelogenous Leukemia/Myelodysplastic Syndrome?

1 Aug 2008

Abstract excerpt

Abstract Context.—The clinical association between loss of the Y chromosome and acute myelogenous leukemia and myelodysplastic syndrome (AML/MDS) has been debated because both phenomena are related to aging. A prior publication suggests that loss of the Y chromosome in more than 75% of cells may indicate a clonal phenomenon that could be a marker for hematologic disease. Objective.—To evaluate the relationship...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Acute Myeloid Leukemia Research
Share to Chronic Myeloid Leukemia Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Retinoids in leukemia and cellular processes

Source

Identifiers

PMID: 18684036
DOI: 10.5858/2008-132-1329-lotyca

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of the Y Chromosome: An Age-Related or Clonal Phenomenon in Acute Myelogenous Leukemia/Myelodysplastic Syndrome?PMID 18684036Read ↗

Molecular genetic evidence of Y chromosome loss in male patients with hematological disordersSemantic proximity Read ↗

Clinical significance of Y chromosome loss in hematologic diseaseSemantic proximity Read ↗

Genomic alterations in patients with somatic loss of the Y chromosome as the sole cytogenetic finding in bone marrow cellsSemantic proximity Read ↗

Myelodysplastic syndromes, aging, and age: correlations, common mechanisms, and clinical implications.Semantic proximity Read ↗

Loss of the Y chromosome from normal and neoplastic bone marrowsSemantic proximity Read ↗

Clinical and biological significance of isolated Y chromosome loss in myelodysplastic syndromes and chronic myelomonocytic leukemia. A report from the Spanish MDS GroupSemantic proximity Read ↗

Aging, hematopoiesis, and the myelodysplastic syndromesSemantic proximity Read ↗

Sex chromosome changes in leukemia: cytogenetics and molecular aspectsSemantic proximity Read ↗

Aging- and Senescence-associated Changes of Mesenchymal Stromal Cells in Myelodysplastic Syndromes.Semantic proximity Read ↗

The route to development of myelodysplastic syndrome/acute myeloid leukaemia in Shwachman‐Diamond syndrome: the role of ageing, karyotype instability, and acquired chromosome anomaliesSemantic proximity Read ↗

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer.Semantic proximity Read ↗

Clonal haemopoiesis in normal elderly women: implications for the myeloproliferative disorders and myelodysplastic syndromesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.