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Article

Sex chromosome changes in leukemia: cytogenetics and molecular aspects

10 Sept 2017

Abstract excerpt

BACKGROUND AND OBJECTIVE: Sex chromosome loss (SCL) can occur in older men as a physiological phenomenon or as an acquired abnormality in leukemia. Loss of chromosome Y and loss of chromosome X are acquired disorders that are mainly observed in patients over 80 years as well as in myeloid and lymphoid malignancies. In this review, we examine the cytogenetic and molecular changes of sex chromosomes in leukemia....

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Share to Chronic Myeloid Leukemia Treatments
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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Identifiers

PMID: 28889783
DOI: 10.1080/10245332.2017.1375063

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