Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detailed understanding of enhanced specific antibody productivity in NS0 myeloma cells

9 Jul 2008

Abstract excerpt

The understanding of how cellular productivity is modulated in cell lines is of significant importance in the biopharmaceutical industry. Often, single molecular mechanisms fail to fully explain how specific antibody productivity is enhanced during proliferation arrest. Previously, we reported that certain physiological changes occur when proliferation is arrested by p21(CIP1) over expression. In this work, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Protein purification and stability
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18683250
DOI: 10.1002/bit.22041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detailed understanding of enhanced specific antibody productivity in NS0 myeloma cellsPMID 18683250Read ↗

Modulation of Cell Cycle for Enhancement of Antibody Productivity in Perfusion Culture of NS0 CellsSemantic proximity Read ↗

Understanding the intracellular effect of enhanced nutrient feeding toward high titer antibody production processSemantic proximity Read ↗

Comparative proteomic analysis of GS‐NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rateSemantic proximity Read ↗

Sustained productivity in recombinant Chinese hamster ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype.Semantic proximity Read ↗

Comparative transcriptome analysis to unveil genes affecting recombinant protein productivity in mammalian cellsSemantic proximity Read ↗

Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell culturesSemantic proximity Read ↗

Specific monoclonal antibody productivity and the cell cycle-comparisons of batch, continuous and perfusion culturesSemantic proximity Read ↗

Functional Parameters of Hybridoma Cells: Methods of Evaluation and Biotechnological RelevanceSemantic proximity Read ↗

Enhancing monoclonal antibody production efficiency using CHO-MK cells and specific media in a conventional fed-batch cultureSemantic proximity Read ↗

OPP Labeling Enables Total Protein Synthesis Quantification in CHO Production Cell Lines at the Single‐Cell LevelSemantic proximity Read ↗

Proteomic Analysis of Bioreactor Cultures of an Antibody Expressing CHOGS Cell Line that Promotes High ProductivitySemantic proximity Read ↗

Development of a stable antibody production system utilizing an Hspa5 promoter in CHO cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.