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Article

Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults.

Diabetologia - 1 Jul 2009

Jonsson A, Renström F, Lyssenko V, Brito E C, Isomaa B, Berglund G, Nilsson P M, Groop L, Franks P W

Abstract excerpt

AIMS/HYPOTHESIS: Recent reports have suggested that genotypes at the FTO locus interact with physical activity to modify levels of obesity-related traits. We tested this hypothesis in two non-diabetic population-based cohorts, the first from southern Sweden and the second from the Botnia region of western Finland. METHODS: In total 2,511 Finnish and 15,925 Swedish non-diabetic middle-aged adults were genotyped...

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Source

Identifiers

PMID: 19373445
DOI: 10.1007/s00125-009-1355-2

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults.PMID 19373445Read ↗

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Physical activity attenuates the effect of the FTO genotype on obesity traits in European adults: The Food4Me study.Semantic proximity Read ↗

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.Semantic proximity Read ↗

Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity.Semantic proximity Read ↗

The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924.Semantic proximity Read ↗

Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity.Semantic proximity Read ↗

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