Article
Survival of the sparsest: robust gene networks are parsimonious.
Molecular systems biology - 1 Jan 2008
Leclerc Robert D
Abstract excerpt
Biological gene networks appear to be dynamically robust to mutation, stochasticity, and changes in the environment and also appear to be sparsely connected. Studies with computational models, however, have suggested that denser gene networks evolve to be more dynamically robust than sparser networks. We resolve this discrepancy by showing that misassumptions about how to measure robustness in artificial networks...
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