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In Vivo Interactome of Helicobacter pylori Urease Revealed by Tandem Affinity Purification

5 Aug 2008

Abstract excerpt

In the human gastric bacterium Helicobacter pylori, two metalloenzymes, hydrogenase and urease, are essential for in vivo colonization, the latter being a major virulence factor. The UreA and UreB structural subunits of urease and UreG, one of the accessory proteins for Ni(2+) incorporation into apourease, were taken as baits for tandem affinity purification. The method allows the purification of protein...

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PMID: 18682379
DOI: 10.1074/mcp.m800160-mcp200

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In Vivo Interactome of Helicobacter pylori Urease Revealed by Tandem Affinity PurificationPMID 18682379Read ↗

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