Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of copy number alterations and its association with pathological features in clear cell and papillary RCC.

Cancer letters - 18 Dec 2008

Matsuda Daisuke, Khoo Sok Kean, Massie Aaron, Iwamura Masatsugu, Chen Jindong, Petillo David, Wondergem Bill, Avallone Michael, Kloostra Stephanie J, Tan Min-Han, Koeman Julie, Zhang Zhongfa, Kahnoski Richard J, Baba Shiro, Teh Bin Tean

Abstract excerpt

We report and characterize the copy number alterations (CNAs) in 35 clear cell and 12 papillary renal cell carcinomas (RCC) using Affymetrix 100K SNP arrays. Novel gain and loss regions are identified in both subtypes. In addition, statistically significant CNA are detected and associated with the pathological features: VHL mutation status, tumor grades, and sarcomatoid component in clear cell RCC and in types 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Papillary
Share to Carcinoma, Renal Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human

Share to DNA Primers

Share to In Situ Hybridization, Fluorescence

Share to Kidney Neoplasms

Share to Polymerase Chain Reaction

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Identifiers

PMID: 18682315
DOI: 10.1016/j.canlet.2008.06.015

Genes

TGFBI
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of copy number alterations and its association with pathological features in clear cell and papillary RCC.PMID 18682315Read ↗

Somatic Copy Number Alterations and Associated Genes in Clear-Cell Renal-Cell Carcinoma in Brazilian PatientsSemantic proximity Read ↗

Genomic copy number alterations in clear cell renal carcinoma: associations with case characteristics and mechanisms of VHL gene inactivationSemantic proximity Read ↗

Multilevel Whole-Genome Analysis Reveals Candidate Biomarkers in Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile.Semantic proximity Read ↗

A Comprehensive Study of Progressive Cytogenetic Alterations in Clear Cell Renal Cell Carcinoma and a New Model for ccRCC Tumorigenesis and ProgressionSemantic proximity Read ↗

Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes.Semantic proximity Read ↗

Comprehensive analysis of somatic copy number alterations in clear cell renal cell carcinoma.Semantic proximity Read ↗

Loss of heterozygosity and copy number abnormality in clear cell renal cell carcinoma discovered by high-density affymetrix 10K single nucleotide polymorphism mapping array.Semantic proximity Read ↗

Genetic clustering of clear cell renal cell carcinoma based on array-comparative genomic hybridization: its association with DNA methylation alteration and patient outcome.Semantic proximity Read ↗

Renal cell tumors with clear cell histology and intact VHL and chromosome 3p: a histological review of tumors from the Cancer Genome Atlas database.Semantic proximity Read ↗

Distinct Genomic Copy Number Alterations Distinguish Mucinous Tubular and Spindle Cell Carcinoma of the Kidney From Papillary Renal Cell Carcinoma With Overlapping Histologic Features.Semantic proximity Read ↗

High‐resolution analysis of DNA copy number alterations and gene expression in renal clear cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.