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Article

Evidence for an ancient BRCA1 mutation in breast cancer patients of Yoruban ancestry.

Familial cancer - 1 Jan 2009

Zhang Bifeng, Fackenthal James D, Niu Qun, Huo Dezheng, Sveen Walmy E, DeMarco Tiffani, Adebamowo Clement A, Ogundiran Temidayo, Olopade Olufunmilayo I

Abstract excerpt

BACKGROUND: BRCA1 recurrent mutations have rarely been assessed in non-founder populations. Still, identifying such mutations could be important for designing genetic testing strategies for high-risk breast/ovarian cancer families in non-founder populations. OBJECTIVE: To determine whether the recurrent BRCA1 Y101X mutation identified in Yoruban breast cancer patients represents a single historical mutation...

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Source

Identifiers

PMID: 18679828
DOI: 10.1007/s10689-008-9205-9

Genes

BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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