Article
Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein H.
The Journal of biological chemistry - 31 Oct 2008
Galdiero Stefania, Falanga Annarita, Vitiello Mariateresa, Raiola Luca, Fattorusso Roberto, Browne Helena, Pedone Carlo, Isernia Carla, Galdiero Massimiliano
Abstract excerpt
Glycoprotein H (gH) of herpes simplex virus type I (HSV-1) is involved in the complex mechanism of membrane fusion of the viral envelope with the host cell. Membrane interacting regions and potential fusion peptides have been identified in HSV-1 gH as well as glycoprotein B (gB). Because of the complex fusion mechanism of HSV-1, which requires four viral glycoproteins, and because there are only structural data...
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